Anti-Human ASIC3 Polyclonal Antibody

This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06349
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human ASIC3.
Specificity Expressed by sensory neurons. Strongly expressed in brain, spinal chord, lung, lymph nodes, kidney, pituitary, heart and testis.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q9UHC3
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:20000
Formulation
Application WB,ELISA
Other Names ACCN 3,Accn3,ACCN3,Acid sensing ion channel 3,Acid-sensing ion channel 3,Amiloride sensitive cation channel 3,Amiloride sensitive cation channel 3 testis,Amiloride-sensitive cation channel 3,ASIC 3,ASIC3,DRASIC,hASIC 3,hASIC3,hTNaC 1,hTNaC1,Modulatory subunit of ASIC 2a,Modulatory subunit of ASIC2a,Neuronal amiloride sensitive cation channel 3,Neuronal amiloride-sensitive cation channel 3,Proton gated cation channel subunit,SLNAC 1,SLNAC1,Testis sodium channel 1,TNaC 1,TNaC1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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