Anti-Human ANP32C Polyclonal Antibody

Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05616
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human PP32R1
Specificity Expressed in activated stem cells, such as mobilized CD34+ cells and cord blood CD34+ cells, but not in resting bone marrow CD34+ cells. Expressed in a variety of neoplastic cell lines, mainly in prostatic adenocarcinoma cell lines. Not expressed in normal prostatic tissue.
Isotype IgG
Reacitivity Human
Clone
Uniprot O43423
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:10000
Formulation
Application WB,ELISA
Other Names Acidic (leucine rich) nuclear phosphoprotein 32 family,member C,Acidic leucine-rich nuclear phosphoprotein 32 family member C,AN32C,ANP32 C,ANP32C,Phosphoprotein 32 related protein 1,Phosphoprotein 32-related protein 1,pp32 related 1,PP32R1,Tumorigenic protein pp32r1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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