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Anti-Human AKR1C1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10599
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human AKR1C1
Specificity Expressed in all tissues tested including liver, prostate, testis, adrenal gland, brain, uterus, mammary gland and keratinocytes. Highest levels found in liver, mammary gland and brain.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q04828
Concentration 0.1 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names 2-dihydrobenzene-1,2-diol dehydrogenase,20 alpha (3 alpha) hydroxysteroid dehydrogenase,20 ALPHA HSD,20 alpha hydroxysteroid dehydrogenase,20-alpha-HSD,20-alpha-hydroxysteroid dehydrogenase,20ALPHAHSD,2ALPHAHSD,AK1C1,AK1C1,AKR1C1,Aldo keto reductase family 1 member C1,aldo-keto reductase C,Aldo-keto reductase family 1 member C1,Aldo-keto reductase family,1 member 1,C9,Chlordecone reductase homolog,Chlordecone reductase homolog HAKRC,DD1,DD1/DD2,DDH,DDH1,Dihydrodiol dehydrogenase 1,Dihydrodiol dehydrogenase 1/2,dihydrodiol dehydrogenase 1,20-alpha (3-alpha)-hydroxysteroid dehydrogenase,dihydrodiol dehydrogenase isoform DD1,Dihydrodiol dehydrogenase,type 1,H37,HAKRC,HBAB,Hepatic dihydrodiol dehydrogenase,High affinity hepatic bile acid-binding protein,High-affinity hepatic bile acid-binding protein,Indanol dehydrogenase,MBAB,MGC8954,Trans-1,Trans-1,2 dihydrobenzene 1,2 diol dehydrogenase,Type II 3 alpha hydroxysteroid dehydrogenase
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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