Anti-Human AKAP1 Polyclonal Antibody

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.AKAP1 (A-Kinase Anchoring Protein 1) is a Protein Coding gene. Among its related pathways are Proton Pump Inhibitor Pathway, Pharmacodynamics and Activation of cAMP-Dependent PKA. GO annotations related to this gene include nucleic acid binding and RNA binding.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03087
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human AKAP 149
Specificity AKAP149 is highly expressed in prostate and small intestine whereas S-AKAP84 is expressed in kidney, pancreas, liver, lung and brain. AKAP149 is also expressed in colon carcinoma.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q92667
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names A kinase anchor protein,A-kinase anchor protein 1,A-kinase anchor protein 149 kDa,AKAP 149,AKAP,Akap1,AKAP1,D-AKAP-1,DAKAP1,Dual specificity A-kinase-anchoring protein 1,mitochondrial,PRKA1,Protein kinase A-anchoring protein 1,Protein kinase A1,S-AKAP84,SAKAP84,Spermatid A-kinase anchor protein 84
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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