Recombinant Mouse FLT3L / Flt3 ligand Protein (Fc tag)

Categories: [Proteins / Peptides]
FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of the hematopoietic progenitors and stem cells. This may help the system to kill cancer cells. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3L controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 -positive classical DCs and their CD103 -positive tissue counterparts.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP05653
Size 20ug,50ug,100ug…
Host HEK293 Cells
Accession P49772-1
Molecular Weight 45.4 kDa
AP_Mol_Weight 56 & 35 kDa
Tag C-Fc
Sequences Met1-Arg188
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names FLT3L
Bioactivity Measured in a cell proliferation assay using BaF3 mouse pro-B cells transfected with mouse Flt-3. The ED50 for this effect is typically 7-30 ng/mL.
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.

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