Recombinant Mouse EphA3 Protein (His tag)

Categories: [Proteins / Peptides]
EPHA3 gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. EPHA3 gene encodes a protein that binds ephrin-A ligands. EPHA3 is involved in the retinotectal mapping of neurons. It may also control the segregation but not the guidance of motor and sensory axons during neuromuscular circuit development.Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy
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Properties

Data Sheet Click for Datasheet
Catalog Number TP05594
Size 20ug,50ug,100ug…
Host HEK293 Cells
Accession NP_796047.2
Molecular Weight 60.2 kDa
AP_Mol_Weight
Tag C-His
Sequences Met1-His541
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names AW492086;Cek4;End3;ETK1;Hek;Hek4;Mek4;Tyro4
Bioactivity 1. Measured by its binding ability in a functional ELISA.2. Immobilized mouse EPHA3-His at 10 µg/mL (100 μL/well) can bind mouse EFNA5-Fc . The EC50 of mouse EFNA5-Fc is 4.9-11.4ng/mL.
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.

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