Recombinant Mouse Cathepsin B Protein

Categories: [Proteins / Peptides]
Cathepsin B (CatB) is an enzymatic protein belonging to the peptidase (or protease) families. It is the first described member of the family of lysosomal cysteine proteases. It is known to process a number of proteins, including pro and active caspases, prorenin and secretory leucoprotease inhibitor (SLPI). It is believed to participate in intracellular degradation and turnover of proteins. Cathepsin B may play a role in activation and inactivation of caspases, activation of renin and inactivation of SLPI, the key steps in apoptosis, angiotensin production, and progression of emphysema, respectively. Cathepsin B may also have a role in invasion and metastasis.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP06149
Size 20ug,50ug,100ug…
Host Human Cells
Accession P10605
Molecular Weight 36.4 kDa
AP_Mol_Weight 32-50 kDa
Tag C-6His
Sequences Met 1-Phe 339
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names Cathepsin B;Ctsb;Cathepsin B1
Bioactivity Measured by its ability to cleave the fluorogenic peptide substrate Z-LR-AMC (R&D Systems, Catalog # ES008). The specific activity is >2,000 pmoles/min/µg.
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.

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