Recombinant Human Transcriptional Repressor CTCF/CTCF Protein

Categories: [Proteins / Peptides]
Transcriptional Repressor CTCF (CTCF) belongs to the CTCF Zinc-Finger Protein family. CTCF contains twelve C2H2-type zinc fingers and interacts with CHD8. CTCF is widely expressed in many tissues, and it is absent in primary spermatocytes. CTCF is involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. CTCF plays an essential role in oocyte and preimplantation embryo development by activating or repressing transcription. In addition, CTCF is also indispensable in the epigenetic regulation and chromatin remodeling.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP05779
Size 20ug,50ug,100ug…
Host E.coli
Accession P49711
Molecular Weight 16.9 kDa
AP_Mol_Weight 33 kDa
Tag
Sequences Met 1-Ile154
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names Transcriptional Repressor CTCF; 11-Zinc Finger Protein; CCCTC-Binding Factor; CTCFL Paralog; CTCF
Bioactivity
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.

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