Recombinant Human T-cell surface antigen CD2 Protein

Categories: [Proteins / Peptides]
T-cell surface antigen CD2 is also known as Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5. It is a protein that in humans is encoded by the CD2 gene. It is a single-pass type I membrane protein. contains 1 Ig-like C2-type domain and 1 Ig-like V-type domain. T-cell surface antigen CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. It is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP06027
Size 20ug,50ug,100ug…
Host Human Cells
Accession NP_001758.2
Molecular Weight 22.5 kDa
AP_Mol_Weight 34 kDa
Tag C-6His
Sequences Lys25-Asp209
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names T-cell surface antigen CD2;Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5.
Bioactivity Measured by its binding ability in a functional ELISA.Immobilized human CD2-His at 10 μg/ml (100 μl/well) can bind human CD58-Fc, The EC50 of human CD58-Fc is 0.04-0.1 μg/ml.
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.

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