Recombinant Human PDCD4/H731 Protein(C-6His)

Categories: [Proteins / Peptides]
Programmed Cell Death Protein 4 (PDCD4) is a member of the PDCD4 family. PDCD4 and EIF4A1 form a heterotrimer. One molecule of PDCD4 binds two molecules of EIF4A1. PDCD4 takes part in apoptosis via inhibiting translation initiation and cap-dependent translation.PDCD4 promotes colonic neoplastic transformation and tumor invasion. PDCD4 is an important target for microrna R-21 in breast cancer cells. Shortage of PDCD4 expression is associated with colorectal cancer. Overexpression of PDCD4 in carcinoid cells results in inhibition of cell proliferation.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP05318
Size 20ug,50ug,100ug…
Host E.coli
Accession Q53EL6
Molecular Weight 17.0 kDa
AP_Mol_Weight 17 kDa
Tag C-6His
Sequences Lys212-Pro357
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names Programmed Cell Death Protein 4; Neoplastic Transformation Inhibitor Protein; Nuclear Antigen H731-Like; Protein 197/15a; PDCD4; H731
Bioactivity
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.

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