Recombinant Human Neurotrophin-3/NT3 Protein

Categories: [Proteins / Peptides]
Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to β-NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequences of mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP05697
Size 20ug,50ug,100ug…
Host E.coli
Accession P20783
Molecular Weight 13.6 kDa
AP_Mol_Weight 14 kDa
Tag
Sequences Tyr139-Thr 257
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names Neurotrophin-3; NT-3; HDNF; Nerve Growth Factor 2; NGF-2; Neurotrophic Factor; NTF3
Bioactivity Measured by its ability to bind Human NTRK2 in functional ELISA.The ED50 for this effect is less than 10 ug/ml.
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.

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