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Recombinant Human Leukocyte Surface Antigen CD47/IAP/OA3 Protein(C-Fc)

Categories: [Proteins / Peptides]
CD47(Integrin-Associated Protein,IAP) is a 40 - 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP06059
Size 20ug,50ug,100ug…
Host Human Cells
Accession Q08722
Molecular Weight 41.9 kDa
AP_Mol_Weight 60 kDa
Tag C-Fc
Sequences Gln19-Pro139
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names Leukocyte Surface Antigen CD47; Antigenic Surface Determinant Protein OA3; Integrin-Associated Protein; IAP; Protein MER6; CD47; MER6
Bioactivity Measured by its ability to bind Human SIRPA in functional ELISA.The ED50 for this effect is less than 200 ng/ml.
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.
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