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Recombinant Human Interleukin-28B/IL-28B/IFN-lambda 3 Protein(C-6His)

Categories: [Proteins / Peptides]
Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP05904
Size 20ug,50ug,100ug…
Host Human Cells
Accession Q8IZI9
Molecular Weight 20.7 kDa
AP_Mol_Weight 19 kDa
Tag C-6His
Sequences Val22-Val196
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names Interleukin-28B; IL-28B; Cytokine Zcyto22; Interferon Lambda-3; IFN-Lambda-3; Interferon Lambda-4; IFN-Lambda-4; Interleukin-28C; IL-28C; IL28B; IFNL3; IFNL4; IL28C; ZCYTO22
Bioactivity Measured by its ability to binding IL10RB used funtional ELISA.The ED50 for this effect is less than 10 ug/ml.
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.
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