Recombinant Human IL7 / interleukin 7 Protein

Categories: [Proteins / Peptides]
IL7, also known as interleukin 7, is a hematopoietic growth factor which belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRß) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes.Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy
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Properties

Data Sheet Click for Datasheet
Catalog Number TP06220
Size 20ug,50ug,100ug…
Host E.coli
Accession NP_000871.1
Molecular Weight 17.5 kDa
AP_Mol_Weight 19 kDa
Tag
Sequences Asp26-His177
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names IL-7;Interleukin-7
Bioactivity Measured by its binding ability in a functional ELISA.Immobilized human IL7 at 10 μg/ml (100 μl/well) can bind human IL7Ra-Fch, The EC50 of human IL7Ra-Fch is 15.2-35.6 ng/ml.2. Measured in a cell proliferation assay using antibody against CD3-activated h
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.

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