Recombinant Human Aldo-Keto Reductase 1C4/AKR1C4 Protein(N-6His)

Categories: [Proteins / Peptides]
Aldo-Keto Reductase 1C4/AKR1C4 is a member of the aldo/keto reductase family that consists of more than 40 known enzymes and proteins. AKR1C4 has highly expressed in Liver. It can catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. AKR1C4 catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-α-Androstan-3-α,17-β-diol (3-α-diol). In addition, AKR1C4 also has some 20-α-Hydroxysteroid Dehydrogenase activity.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP05903
Size 20ug,50ug,100ug…
Host E.coli
Accession P17516
Molecular Weight 39.3 kDa
AP_Mol_Weight 26&38 kDa
Tag N-6His
Sequences Met 1-Tyr323
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names Aldo-Keto Reductase Family 1 Member C4; 3-Alpha-HSD1; 3-Alpha-Hydroxysteroid Dehydrogenase Type I; Chlordecone Reductase; CDR; Dihydrodiol Dehydrogenase 4; DD-4; DD4; HAKRA; AKR1C4; CHDR
Bioactivity
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.

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