14-3-3 τ Anti-Human Antibody (Clone At1A1)

The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ and η that have been identified in mammals. The 14-3-3 tau, a subtype of the 14-3-3 family of proteins, was found in T Cells, brain and testes. This 14-3-3 tau is upregulated in patients with amyotrophic lateral sclerosis.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01031
Size 100 µL
Host Type Mouse
Immunogen Recombinant human 14-3-3 tau (1-245aa) purified from E. coli
Specificity
Isotype Mouse IgG1 heavy chain and kappa light chain.
Reacitivity Human
Clone Anti-human 14-3-3 tau mAb, clone AT1A1, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human 14-3-3 tau protein.
Uniprot
Concentration 1 mg/mL
Dilution
Formulation Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application ELISA, WB, ICC/IF, Flow cytometry
Other Names 14-3-3 Tau Anti-Human Antibody
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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