GSS Antibody (Clone AT12F2)

Categories: [ Antibodies][ Monoclonal Antibodies]

Glutathione synthetase, also known GSS, is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine, to form glutathione. Defects in GSS are the cause of glutathione synthetase deficiency (GSS deficiency); also known as 5-oxoprolinuria or pyroglutamic aciduria. It is a severe form characterized by an increased rate of hemolysis and defective function of the central nervous system.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	MA01298
Size	100 µL
Host Type	Mouse
Immunogen	Recombinant human GSS (1-474aa) purified from E. coli
Specificity
Isotype	Mouse IgG1, k
Reacitivity	Human
Clone	Anti-human GSS mAb, clone AT12F2, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human GSS protein
Uniprot
Concentration	1mg/ml
Dilution
Formulation	Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application	ELISA, WB, ICC/IF
Other Names	Glutathione synthetase, GSHS, GSH synthetase
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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GSS Antibody (Clone AT12F2)

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