Frataxin Antibody (Clone AT10E11)

Categories: [ Antibodies][ Monoclonal Antibodies]

Frataxin, also known as FXN, is an iron binding protein which belongs to FRATAXIN family. It is an anti-apoptotic protein which prevents mitochondrial damage, reactive oxygen species production and act as either an iron chaperone or an iron storage protein. Frataxin is localized to the mitochondrion and regulating mitochondrial iron transport and respiration. Defects in this protein cause Friedreich ataxia.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	MA01257
Size	100 µL
Host Type	Mouse
Immunogen	Recombinant human Frataxin (42-210aa) purified from E. coli
Specificity
Isotype	IgG1, k
Reacitivity	Human
Clone	Anti-human Frataxin mAb, clone AT10E11, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Frataxin protein.
Uniprot
Concentration	1 mg/ml
Dilution
Formulation	Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application	ELISA, WB, Flow cytometry, ICC/IF
Other Names	CyaY, FA, FARR, FRDA, X25, FXN, Friedreich ataxia protein.
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Frataxin Antibody (Clone AT10E11)

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