GARS Monoclonal Antibody (Clone AT4E10)

抗人甘氨酰tRNA合成酶单克隆抗体

GARS, also known as glycyl-tRNA synthetase, is one of the aminoacyl-tRNA synthetase that charge tRNAs with their cognate amino acids. Defects in the gene encoding GlyRS is the cause of Charcot-Marie-Tooth disease type 2D (CMT2D), which is an autosomal dominant inherited disease characterized by severe weakness, atrophy and absence of deep tendon reflexes in the upper extremities. Defects in the GlyRS gene is also the cause of distal hereditary muscular neuropathy type V (HMN5), a disease similar to CMT2D, though the distal sensory involvement is less severe in HMN5 patients.
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基本信息

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货号 MA01272
规格 100 µL
宿主 Mouse
免疫原 Recombinant human GARS (43-289aa) purified from E. coli
特异性
亚型 IgG1,k
反应性 Human
克隆 Anti-human GARS mAb, clone AT4E10, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human GARS protein.
Uniprot
浓度 1 mg/mL
推荐稀释度
配方 Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
应用范围 ELISA, WB, ICC/IF
别名 Glycyl-tRNA synthetase, CMT2D, DSMAV, GlyRS, HMN5, SMAD1.
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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