CD3E Monoclonal Antibody (Clone AT3H3)

抗人CD3E单克隆抗体

The T cell antigen receptor (TCR) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. Much of this signaling process can be attributed to a multi subunit complex of proteins that associates directly with the TCR. This complex has been designated CD3 (cluster of differentiation 3). It is composed of five invariant polypeptide chains that associate to form three dimers. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
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基本信息

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货号 MA01158
规格 100 µL
宿主 Mouse
免疫原 Recombinant human CD3E (23-126aa) purified from E. coli
特异性
亚型 IgG1,k
反应性 Human
克隆 Anti-human CD3E mAb, clone AT3H3, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CD3E protein.
Uniprot
浓度 1 mg/mL
推荐稀释度
配方 Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
应用范围 ELISA, WB, Flow cytometry, ICC/IF
别名 T-cell surface glycoprotein CD3 epsilon chain, T3E, TCRE.
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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