14-3-3 β Anti-Human Antibody (Clone J2E9)

The 14-3-3 family plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, β, γ, ε, σ, ζ, τ and η that have been identified in mammals. The 14-3-3 beta, a subtype of the 14-3-3 proteins, was found in B Cells, brain and liver etc. This 14-3-3 beta has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery.
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基本信息

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货号 MA01016
规格 100 µL
宿主 Mouse
免疫原 Recombinant human 14-3-3 beta (1-246aa) purified from E. coli
特异性
亚型 Mouse IgG2a heavy chain and kappa light chain
反应性 Human
克隆 Anti-human 14-3-3 beta mAb, clone J2E9, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human YWHAB protein.
Uniprot
浓度 1 mg/ml
推荐稀释度
配方 Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
应用范围 ELISA, WB.
别名 Anti-14-3-3 β Protein.
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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