Home / Products / proteins / CENPM, 1-180aa, Human, His tag, E.coli

CENPM, 1-180aa, Human, His tag, E.coli

Categories: [Proteins / Peptides]
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays nucleosomes in which CENPA replaces histone H3. CENPM is an additional factor required for centromere assembly. Recombinant human CENPM protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP01579
Size 100 µg
Host E.coli
Accession
Molecular Weight 22 kDa (203aa), confirmed by MALDI-TOF
AP_Mol_Weight
Tag N-6His
Sequences
Purity > 95% by HPLC
Concentration 0.25 mg/ml (determined by Bradford assay)
Formulation Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT.
Other Names Centromere protein M isoform a, bK250D10.2, C22orf18, CENP-M, PANE1
Bioactivity
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.
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