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CDK4 Antibody (Clone AT6D10)

Categories: [ Antibodies][ Monoclonal Antibodies]
Cyclin-dependent kinase 4, also known as CDK4, belongs to the cyclin-dependent kinases (CDK) family. CDKs are a family of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells. CDK4, in complex with D-type cyclins, is thought to regulate cell growth during the G1 phase of the cell cycle. This association with a D-type cyclin up-regulates CDK4 activity, whereas binding to the CDK inhibitor p16 down-regulates CDK4 activity.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01166
Size 100 µL
Host Type Mouse
Immunogen Recombinant human CDK4 (1-303aa) purified from E. coli
Specificity
Isotype IgG2a, k
Reacitivity Human
Clone Anti-human CDK4 mAb, clone AT6D10, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CDK4 protein.
Uniprot
Concentration 1 mg/ml
Dilution
Formulation Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application ELISA, WB.
Other Names Cyclin-dependent kinase 4, CMM3, PSK-J3.
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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