CDK2AP1, 1-115aa, Human, His tag, E. coli

CDK2AP1 is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. Also, interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	TP01558
Size	100 µg
Host
Accession
Molecular Weight	16.6kDa (152aa)
AP_Mol_Weight
Tag	N-6His
Sequences	MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSHMSYKPNLAAHMPAAALNAAGSVHSPSTSMATSSQYRQLLSDYGPPSLGYTQGTGNSQVPQSKYAELLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARGLVRECLAETERNARS
Purity	> 95% by HPLC
Concentration	0.25 mg/ml (determined by Bradford assay)
Formulation	Liquid. 20mM Tris-HCl buffer (pH8.0) containing 50% glycerol, 2mM DTT
Other Names	Cyclin-dependent kinase 2 associated protein 1, CDKAP1, DOC1
Bioactivity
Storage	Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript	For research use only, not for use in diagnostic procedures.

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CDK2AP1, 1-115aa, Human, His tag, E. coli

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