ASNA1 Antibody (Clone AT2A1)

ASNA1, also as known as ARSA and TRC40, is the human homolog of the bacterial arsA, a member of the ATPase superfamily. ArsA and ArsB have been postulated to form a membrane complex which functions as an anion-translocating. It recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ArsA hydrolyses ATP in the presence of its anionic substrate antimonite and produces resistance to arsenite and antimonite. The active form of ArsA is a homodimer with four nucleotide binding sites, two from each monomer.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01098
Size 100 µL
Host Type Mouse
Immunogen Recombinant human ASNA1 (1-348aa) purified from E. coli
Specificity
Isotype IgG2b,k
Reacitivity Human
Clone Anti-human ASNA1 mAb, clone AT2A1, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ASNA1 protein.
Uniprot
Concentration 1mg/ml
Dilution
Formulation Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application ELISA, WB, Flow cytometry, ICC/IF
Other Names ATPase ASNA1, ARSA-I, ARSA1, ASNA-I, GET3, hASNA-I, TRC40.
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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