Anti-Human/Mouse Acetyl-KAT2B (Lys428) Polyclonal Antibody

Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01438
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the human PCAF around the acetylation site of K428.
Specificity Ubiquitously expressed but most abundant in heart and skeletal muscle.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q92831
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:20000
Formulation
Application WB,ELISA
Other Names CAF,CREBBP associated factor,GCN5,GCN5L,GCN5L1,Histone acetylase PCAF,Histone acetyltransferase KAT2B,Histone acetyltransferase PCAF,K(lysine) acetyltransferase 2B,KAT2B,KAT2B,Lysine acetyltransferase 2B,P,P/CAF,p300/CBP associated factor,P300/CBP-associated factor,Pcaf
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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